
NRS Therapy with CRYOFOS unlocks the body’s innate capacity to overcome pain and heal itself.
Neuro Reflex Stimulation (NRS) uses hyperbaric medical CO₂ gas to apply gentle pressure while delivering intense cold therapy. Drastic and abrupt reduction in the surface temperature of the skin causes a “Thermal Shock” that, when combined with the pressure from the gas, produces a variety of beneficial physiological effects using the body’s own resources to combat pain and promote healing.
SENSORY RECEPTORS OF SKIN
Sensory receptors in 1 cm² of skin:

200
Pain

25
Pressure

13
Cold

2
Heat
Besides pain, our skin responds most efficiently to sensations of pressure and cold.

Cryofos Cryotherapy machines target 19X as many sensors on skin as laser therapy!
THERMAL SHOCK: THE CATALYST
The abrupt and drastic lowering of the skin’s surface temperature is called a Thermal Shock.
CRYOFOS delivers intense cold therapy using medical CO₂ gas. From its pressurized, liquid state in the cylinder, the gas emerges from the nozzle of the treatment gun as a fine spray hitting the skin at a temperature of -78° C and cooling the treated area to between 2° C and 4° C in under 30 seconds. This abrupt and drastic temperature change, called a Thermal Shock, triggers a neuro-reflexive response in the body.
The stream of gas from the CRYOFOS treatment gun also applies up to 2 bars of pressure to the treatment area. The combination of this pressure and Thermal Shock is the key to NRS Therapy.
